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Physiochemical property of opioids and spinal analgesia

Volume No : Volume: 02 Issue : 7 Year : 2014 Page No: 347-349

Authors : Rakesh Kumar and Pallavi Sharma

Abstract :

It has been more than two decades since neuraxial opioids first underwent rigorous clinical study for use in humans. The intraspinal route of administration is now commonly used to administer anesthetics and analgesics. Addition of opioids to intraspinal administered local anesthetic provides an effective and prolonged analgesia. However, the physiochemical properties of opioids may influence the onset and duration of opioid analgesia.

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