Author Guidelines
Download Copyright

Phytochemical and antioxidant activity of ethanolic barkextract of Nyctanthes arbor- tristis Linn

Volume No : Volume: 01 Issue : 3 Year : 2013 Page No: 172-184

Authors : Sonu Sharma, Ayaz Ahmad, Seema Gupta

Abstract :

Nyctanthes arbor-tristis Linn family Nyctantheaceae is widely distributed and easily available in the nature, therapeutic use of this plant is detailed in Charaka samhitha, Sushrutha samhita and other traditional systems of medicine. The seeds are cooling and astringent and are useful in vitiated condition of pitta. Seeds are useful in bilious disorders, yield fatty oil used as an illuminant. Oil from seed is used for poisonous bites, bowel complaints, epilepsy and for blackening the hair. Bark has expectorant activity and has the power of removing pains and aches. The drug is also used as hepatoprotective. The dried leaves were subjected to successive extraction using different solvent such as petroleum ether, chloroform, ethyl acetate, and methanol. These solvent extracts were subjected to a phytochemical evaluation to detect the different chemical principle present i.e. carbohydrates, protein, amino acids, steroids, glycosides, alkaloids, tannins, and phenolic compounds and to carry out chromatographic evaluation to isolate the chemical compounds. The present study was aimed at chromatographic evaluation of Nyctanthes arbor-tristis Linn leaves methanol, petroleum ether extract of leaves of Nyctanthes arbor-tristis Linn was screened in-vivo antioxidant investigations. The Antioxidant activity of the various extracts of bark of Nyctanthes arbor-tristis Linn was evaluated by various methods. In-vivo screening antioxidant shows significant activity in ethanolic extract of 100 mg/kg and 200 mg/kg dose when compared with standard drug silymarin. Thus, it may conclude that Nyctanthes arbor-tristis Linn leaves has marked antioxidant property.

Full Text PDF