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Antimetastatic therapeutics according to metastatic cascade: An overview

Volume No : (2015) Volume: 03 Issue : 20 Year : 2015 Page No: 716-726

Authors : Da-Yong Lu, Ting-Ren Lu

Abstract :

More than 90% of cancer deaths are caused by cancer metastasis. Since cancer metastasis is the main cause of human deaths, antimetastatic treatment studies should play decisive roles for elongation of cancer patients’ survival. Past three decades, despite cancer metastatic biological or pathological theories have been proved again and again by new biological techniques, translational or clinical studies against neoplasm metastasis are less fruitful. Facing these challenges, promoting the studies of all these new attempts might change the landscape of metastasis treatments. This overview, one of these attempts—optimizing antimetastatic drug efficacies by one possible strategy is highlighted.

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