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Is Saccharomyces boulardii an ideal probiotic in managementof gastrointestinal diseases?: A review

Volume No : (2022) Volume: 10 Issue : 46 Year : 2022 Page No: 41

Authors : Sagar N. Ande, Kartikeya R. Mudholkar, Ravindra L. Bakal, Mahendra D. Kshirsagar

Abstract :

Probiotics are beneficialbacteria. A substance released by one organism that promotes the development ofanother. As well as living microorganisms that encourage the development ofanother probiotic as well as live microorganisms that confer a health advantageon the host on condition that in sufficient proportions. Multiple mechanisms ofaction against infections are among the advantages of probiotic treatment. Itincludes things such as improving gut barrier function, antimicrobial peptidesynthesis, pathogen competitive exclusion, immunological modulation, and tropicimpact. The capacity of the probiotic to engage with the host’s natural defensesystem, resulting in increased survival of the mark organ and a favorablerisk-benefit ratio. It demonstrated ability to prevent and treat some gastrointestinalinfections such as Helicobacter pylori, fungemia, ulcerative colitis, andirritable bowel disease. Its effective use in gastric infection, immunocompromisedpatients, and also decrease patient’s exposure to antimicrobials. As well as,it used as good nutritive food for gastrointestinal tract. Clinical studies areclearly showed its safety and efficacy of these agents. Improved gut barrierfunctioning, pathogen inhibition, antimicrobial peptide production, immunologicalmodulation, and trophic benefits have all been related to its probioticeffectiveness. This research summarizes the significance ofSaccharomycesboulardii in various pathways, as well as the multifactorialbehavior of how yeast affects the host microbiota as well as function ofintestine.

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