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Efficacy of Genpar (paracetamol 1000 mg) infusion in the treatment of fever associated with viral, amoebic, bacterial infections, pneumonia, and enteric fever

Volume No : (2022) Volume: 10 Issue : 46 Year : 2022 Page No: 1- 3

Authors : Sanjay Chandak1, Satish Bhise1, Ramesh Pawar, Rahul Bhutada, C. Dinesh, Pankaj Mittal

Abstract :

Background: Feveris a common problem in adults visiting the casualty setting. Extensive studies havebeen done in children comparing the efficacy of various antipyretics. However,studies on the efficacy of antipyretic drugs in adults are very scarce.

Aim:The present study evaluated the efficacy of genpar (Paracetamol 1000 mg)infusion for the treatment of fever associated with viral, amoebic, bacterialinfections, pneumonia, and enteric fever.

Methods: This prospectivestudy was carried out at multicenter between September 2021 and January 2022.Patients irrespective of age and sex with leading sign of fever (oraltemperature >38.5°C) were included in the study. Oral temperature wasrecorded at 30–35 min, 40–45 min, 60–65 min, and 90–95 min after drugadministration.

Results: Mean age of the patients was 31.46 ± 15.42years. About 62% of patients were aged between 11 and 30 years. About 65% ofthe patients were males. The most common complaint was headache (49%) followedby fever (46%) and body pain (44%). The baseline oral temperature was 102.79 ±0.68°F. There was a significant reduction in body temperature at 30–35 min,40–45 min, 60–65 min, and 90–95 min when compared to baseline body temperature(P < 0.01).

Conclusion: Paracetamol IV infusion can beeffective in immediate temperature control in emergency settings.

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