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Clinical profile of patients with alcoholic liver disease in Rural Maharashtra

Volume No : (2021) Volume: 09 Issue : 44 Year : 2021 Page No: 76-79

Authors : Vedant Rajendraprasad Awasthi, Janhavi Jaywant Deshpande, Jaywant Vasantrao Deshpande

Abstract :


Background: Thespectrum of alcohol-related liver injury varies from simple steatosis tocirrhosis. These are often grouped into three histological stages of alcoholicliver disease (ALD): fatty liver or simple steatosis, alcoholic hepatitis, andcirrhosis of liver. Aim: The study was conducted to assess the clinicalprofile of ALD in rural population. Patients and Methods: In thisprospective hospital-based cross sectional study, patients admitted withalcohol-related liver injury included. Assessment of clinical presentationswith hematological, biochemical parameters, and evaluation of imaging patternsby ultrasonography of Abdo-pelvis was done in all patients. Uppergastro-duodenal (UGD) endoscopy performed in 40 % of patients. Ascitic fluid analysiswas in done 68% patients with ascites. Results: Study revealed thatmales are more affected than females and majority were in the age group of31–40 years. Majority of the patients (46%) were consuming 40 to 60 grams ofalcohol/day and majority of the patients were consuming alcohol for duration of16–20 years (26%). Transudative ascites secondary to portal hypertension wasthe most common finding seen in 54%, followed by jaundice and pallor. UGDendoscopy revealed esophageal varices in 65.5% patients. Conclusion: Wecould conclude that progressive alcoholic liver injury was mainly seen inmiddle aged males. Correlation of clinical, biochemical, and ultrasonographicfindings helps in staging of Liver damage. The severity of liver damage wasdirectly related to the quantity and duration of alcohol consumption

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